Background: The alpha and beta loci determine the structure of the 2 types of polypeptide chains in the adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Absence of beta chain causes beta-zero-thalassemia whereas mutant beta globlin causes sickle cell anemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia.
Description: Rabbit polyclonal to Hemoglobin Beta
Immunogen: KLH conjugated synthetic peptide derived from Hemoglobin Beta
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 16 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
