Background: The Iroquois homeobox gene family of transcription factors regulate various aspects of embryonic development, including anterior/posterior and do-sal/ventral axis patterning and regionalization in both vertebrate and invertebrate central nervous systems. The Iroquois family is comprised of two groups termed IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes IRX1, IRX2 and IRX4, and the IRXB group consists of IRX3, IRX5 and IRX6. IRX6 (Iroquois related homeobox 6), also known as IRXB3 (homeodomain protein IRXB3), is a 438 amino acid nuclear protein belonging to the Iroquois homeobox family. IRX6 contains one homeobox DNA-binding domain and is encoded by a gene located on mouse chromosome 8 C5.
Description: Rabbit polyclonal to IRX6
Immunogen: KLH conjugated synthetic peptide derived from IRX6
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 48 kDa;
·Immunohistochemistry (Frozen/paraffin tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
