Background: ELMO1 is involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. ELMO1 acts in association with DOCK1 and CRK and was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. It is belived to enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Description: Rabbit polyclonal to ELMO1
Immunogen: KLH conjugated synthetic peptide derived from ELMO1
Specificity: ·Reacts with Human, Mouse, Rabbit, Cow, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 30 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/100-500;
·Immunocytochemistry: 1/200;
·ELISA: 1/1000;
·Optimal working dilutions must be determined by the end user.
