Background: Syntenin-2, also known as SDCBP2 (syndecan binding protein (syntenin) 2), ST-2 or SITAC18, is a 292 amino acid protein that contains two PDZ (DHR) domains and functions as either a monomer or a homodimer that interacts with syntenin-1. Multiple isoforms of syntenin-2 exist and are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Description: Rabbit polyclonal to Syntenin 2
Immunogen: KLH conjugated synthetic peptide derived from Syntenin 2
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 32 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
