Background: GLT1D1 (glycosyltransferase 1 domain-containing protein 1) is a 346 amino acid secreted protein belonging to the glycosyltransferase 1 family. Existing as three alternatively spliced isoforms, GLT1D1 maps to human chromosome 12q24.33. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and kniest dysplasia. Noonan syndrome, which is characterized by heart and facial developmental defects and is caused by a mutant form of the PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, as well as the natural killer complex gene cluster, which encodes C-type lectin proteins that mediate the NK cell response to MHC I interaction.
Description: Rabbit polyclonal to GLT1D1
Immunogen: KLH conjugated synthetic peptide derived from GLT1D1
Specificity: ·Reacts with Human, Mouse, Pig, Dog and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 38 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
