Background: Intermediate filaments are composed of two-chain, a-helical, coiled-coil molecules arranged on an imperfect helical lattice. They have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is a general marker of cells originating in the mesenchyme and is frequently co-expressed with other members of the intermediate filament family, such as the cytokeratins, in certain neoplasms. Vimentin and Desmin, a related class III intermediate filament, are both expressed during skeletal muscle development. Desmuslin links Desmin to the extracellular matrix and provides structural support in muscle. HOM-TES-103, also known as intermediate filament family orphan 1 (IFFO1), is a 559 amino acid protein that belongs to the intermediate filament family. Ubiquitously expressed, HOM-TES-103 exists as seven alternatively spliced isoforms.
Description: Rabbit polyclonal to IFFO
Immunogen: KLH conjugated synthetic peptide derived from IFFO
Specificity: ·Reacts with Human, Mouse and Rat.
·Isotype: IgG
Application: ·Western blotting: 1/100-500. Predicted Mol wt: 62 kDa;
·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;
·Immunocytochemistry/Immunofluorescence: 1/100;
·Immunoprecipitation: 1/50;
·ELISA: 1/500;
·Optimal working dilutions must be determined by the end user.
