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SPTBN1 antibody, 血影蛋白β2抗體

 
編 號(hào) PR-6619
產(chǎn)品名稱 SPTBN1 antibody, 血影蛋白β2抗體
規(guī) 格 0.2ml
價(jià) 格 1980元
應(yīng) 用 IHC,WB,ELISA,ICC,IP,IF
品 牌 Hopebiot

詳細(xì)信息: 說(shuō)明書下載

Background:  Spectrin is an actin binding protein that is a major component of the cytoskeletal superstructure of the erythrocyte plasma membrane. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin αI and spectrin βI are present in erythrocytes, whereas spectrin αII (also designated fodrinα) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin β II, which is involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus a candidate for the calcium-dependent movement of the cytoskeleton at the membrane.The human SPTBN1 gene maps to chromosome 2p21 and encodes the nonerythroid form of β-spectrin.

Description: Rabbit polyclonal to SPTBN1

Immunogen: KLH conjugated synthetic peptide derived from SPTBN1

Specificity:  ·Reacts with Human, Mouse and Rat.

·Isotype: IgG

Application:  ·Western blotting: 1/100-500. Predicted Mol wt: 274 kDa;

·Immunohistochemistry (Paraffin/frozen tissue section): 1/50-200;

·Immunocytochemistry/Immunofluorescence: 1/100;

·Immunoprecipitation: 1/50;

·ELISA: 1/500;

·Optimal working dilutions must be determined by the end user.

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